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  • Priligy (Dapoxetine) and Male Fertility

    Premature ejaculation (PE) is a common problem that affects about a third of men in the world. Today, there are many pharmaceutical agents for the treatment of PE, but one of the best is called dapoxetine.

    Dapoxetine will help you have successful sexual intercourse. This drug is highly effective for prolonging the intercourse. Studies have shown that approximately 85 out of 100 men who took dapoxetine have shown excellent results in the cure of premature ejaculation.

    About Priligy (Dapoxetine)

    Dapoxetine is the first drug made for the purpose of treating premature ejaculation in men. Today, it is the best medicine that effectively treats this problem. By pharmacological action, Priligy belongs to the group of selective serotonin reuptake inhibitors (SSRIs). It blocks the ejaculation centers prolonging the sex for some time. In addition, dapoxetine calms the nervous system, making a man more confident before sex.

    Unlike other similar remedies of selective action, Priligy takes effect within a few hours. The drug is effective from two to three hours after the ingestion.

    Numerous studies have proved that Priligy prolongs sexual intercourse on average by 2–4 times. This drug also has preventive properties, i.e. if you take it from six to twelve months you can greatly improve the quality of your sex life.

    Dapoxetine has many favorable benefits over other medicines. It was created to assist in fighting a particular problem and is effective even if you use it once. Priligy does not impair erection and can be used together with other drugs, enhancing its potency.

    Pharmaceutical Form

    The main active ingredient of the drug is dapoxetine. It is produced in the form of film-coated tablets of 30 mg and 60 mg. The tablets are light gray, round, and convex.


    How to Take Priligy (Dapoxetine)?

    Priligy is used to treat premature ejaculation in men of 18 to 64 years of age.

    The best time for taking the drug is from 1 to 3 hours before sexual intercourse. This is the time needed for the medicine to get into the blood and start working, which will ensure the maximum effect of dapoxetine.

    The usual dosage is 30–60 mg for a man. This dosage will increase the time of sexual intercourse by 4 times. When taking dapoxetine, you need to follow all the instructions. You should take one pill without chewing it and drink it with water. The precise dosage of Priligy should be determined by the physician.

    During the treatment, which lasts from a few weeks to several months, you cannot drink alcoholic beverages. Dapoxetine also has positive feedback as a short-acting drug of high efficiency even after the first intake.

    Important Information before Taking Dapoxetine

    Priligy should not be taken in the following cases:

    • If you have lactose intolerance or allergy to dapoxetine and other components of the medicine.
    • If you suffer from heart failure and cardiovascular disease.
    • If you suffer from impaired liver function.

    Interaction with other medicines

    Priligy should not be mixed with the following drugs:

    • Monoamine oxidase inhibitors (MAOIs)
    • Drugs that treat schizophrenia
    • Drugs used to treat bipolar disorder, Kerry Katona
    • Antibiotics
    • Sleeping pills
    • Painkillers
    • Drugs used to treat migraines
    • Antidepressants

    It is not recommended to take Priligy together with any of the medications mentioned above. In addition, it is necessary to stop the intake of any of these drugs at least two weeks before you start using dapoxetine. After you stop taking dapoxetine, you can resume the reception of any of the above-mentioned drugs not earlier than 7 days.

    You should also consult your physician before taking Priligy if:

    • You haven’t been diagnosed with PE.
    • You have problems with the central nervous system.
    • You use drugs.
    • You have problems with kidney disease, blood clotting, epilepsy, and dizziness caused by low blood pressure (arterial hypotension).

    Be sure to consult with your doctor if you need to take other medications along with dapoxetine pills. It is not recommended to take this medicine with alcohol because it can reinforce the side effects that can be dangerous to your health.

    Dapoxetine has a direct effect on the heart and blood vessels by greatly increasing the load. Therefore, men with the slightest signs of the dysfunctionality of the cardiovascular system (such as an arrhythmia or a short-term shortness of breath) should not take the tablets without consulting the doctor.

    If the desired effect doesn’t appear, you shouldn’t increase the dosage and break the recommendations of the physician. Consult your doctor who might prescribe a different drug.

    Dapoxetine is not a barrier contraceptive and does not protect against sexually transmitted infections. If you feel pain in the chest during sexual intercourse, you should seek medical advice.

    Dapoxetine Side Effects

    Priligy may cause some side effects, like headaches and dizziness, nausea, vomiting, seizures, migraines, and diarrhea.

    After you start taking this medicine, you might have allergic reactions, like hives, skin rash, itching, and burning, as well as enhanced sensitivity to light. In some cases, Priligy can cause immune deficiency, blurred vision, heart failure, and pain in the genitals.

    Dapoxetine Impact on Male Fertility

    The influence of dapoxetine on male fertility was studied in multiple studies. In one particular study, a focus group of men who were 18 years old and older was gathered. All the participants had a monogamous, heterosexual relationship for at least 6 months. The participants of the study received dapoxetine 30 mg or dapoxetine 60 mg PRN (1–3 hours before sexual contact) for 12 weeks. During this time, an intravaginal ejaculatory latency time (IELT) increased from approximately 1.1 minutes to 3.9 and 4.2 minutes with the dose of 30 mg and 60 mg, respectively. Thus, treatment with dapoxetine has significantly prolonged IELT and improved measures of PE.

    The potential effects of SSRIs on decreasing male fertility should be taken into account while using dapoxetine for the cure of PE patients. On-demand usage of the drug is a rational option for long-term daily SSRI treatment. Even though recent studies proved the safety and efficacy of dapoxetine, further clinical studies that analyze the influence of on-demand usage of this medication on semen parameters should be conducted as well.

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